WebWhat Is Smoldering Multiple Myeloma? . Smoldering multiple myeloma (SMM) is a condition in which there are higher-than-normal levels of M-protein and plasma cells in your bone marrow. Even though SMM does not cause the signs and symptoms of multiple myeloma, most people with SMM will eventually develop multiple myeloma. WebThat's because it's often difficult to diagnose multiple myeloma until it's progressed. But the earlier you catch it, the better your chances are. Early-stage diagnosis. For the 5% of people who ...

Smoldering Multiple Myeloma: Symptoms, Causes, …

WebJul 22, 2024 · Monoclonal gammopathy of undetermined significance (MGUS) is a condition in which an abnormal protein — known as monoclonal protein or M protein — is in your blood. This abnormal protein is formed within your bone marrow, the soft, blood-producing tissue that fills in the center of most of your bones. The disorder occurs most … WebDec 12, 2024 · Multiple myeloma (MM) is typically characterized by the neoplastic proliferation of plasma cells producing a monoclonal immunoglobulin. The plasma cells proliferate in the bone marrow and can result in extensive skeletal destruction with osteolytic lesions, osteopenia, and/or pathologic fractures. The diagnosis of MM is often suspected … bomber field eureka ca

Smoldering Multiple Myeloma: Diagnosis, Testing & Treatment

WebDec 19, 2013 · Smoldering multiple myeloma (SMM) was initially recognized in the 1980s. 1 It bridged the gap between monoclonal gammopathy of undetermined significance (MGUS; a mostly premalignant disorder) and active multiple myeloma (MM). The classification of SMM is based on levels of circulating monoclonal immunoglobulin, bone … WebDec 14, 2024 · Myeloma cells inhibit your body's ability to fight infections. Bone problems. Multiple myeloma can also affect your bones, leading to bone pain, thinning bones and … WebMultiple myeloma is a cancer of plasma cells. Normal plasma cells are found in the bone marrow and are an important part of the immune system. The immune system is made … gmp development chicago