Cst fam134b

Author: khkw

August undefined, 2024

WebMay 30, 2024 · FAM134B/RETREG1 is a selective ER-phagy receptor that regulates the size and shape of the endoplasmic reticulum. The structure of its reticulon-homology domain (RHD), an element shared with other... WebFeb 21, 2024 · FAM134B controls ER turnover by specific binding to microtubule-associated protein 1 light chain 3B (MAP1LC3B), which in turn binds to the phagophore membrane …

Adjusted amount due: $6,456 - IRS

WebCommunity School 134 is a NYC DOE public school in District 12, Bronx. WebMay 17, 2024 · Four ER-resident proteins (FAM134B, CCPG1, SEC62, and RTN3) have been identified as ER-resident cargo receptors, which contain LC3-interacting regions. In this study, we identified an N … jane russell in the outlaw

FAM134B (E8Y9R) Rabbit mAb Cell Signaling Technology

WebOct 28, 2024 · In contrast, FAM134B may rather act as a tumor suppressor, since FAM134B mutations have been frequently found in colorectal adenocarcinoma, and esophageal squamous cell carcinoma [41, 43, 73]. WebFeb 19, 2024 · FAM134B was the first and so far the best characterized ER-phagy receptor (Khaminets et al, 2015). FAM134B is an intramembrane ER-resident protein that contains a LIR domain and a reticulon homology domain (RHD), which consists of two membrane-embedded hydrophobic regions bridged by a flexible cytoplasmic linker ... WebFeb 19, 2024 · FAM134B was the first and so far the best characterized ER-phagy receptor (Khaminets et al, 2015). FAM134B is an intramembrane ER-resident protein that contains a LIR domain and a reticulon homology … jane russell at the beach

RCSB PDB - 7FB5: Crystal structure of FAM134B/GABARAP complex

Entry - *613114 - RETICULOPHAGY REGULATOR 1; RETREG1

WebOct 13, 2015 · Mutant FAM134B proteins that cause sensory neuropathy in humans (HSAN2B; 613115) are unable to act as ER-phagy receptors. Consistently, disruption of Fam134b in mice causes expansion of the ER, inhibits ER turnover, sensitizes cells to stress-induced apoptotic cell death, and leads to degeneration of sensory neurons. WebApr 11, 2024 · Crucially, to confirm that endogenous FAM134B flux follows a similar trend to the overexpressed reporter, we looked at FAM134B localization in PDAC cells upon BafA1 treatment (Figure 4D). Indeed, FAM134B puncta accumulation after autophagy block indicates high basal turnover rate of the receptor in line with our observation with the … lowest paid major league baseball playersWebFAM134B Attenuates Seizure‑Induced Apoptosis and Endoplasmic Reticulum Stress in Hippocampal Neurons by Promoting Autophagy Nanchang Xie 1 · Yingjiao Li 1 · Cui Wang 2 · Yajun Lian 1 · Haifeng Zhang 1 · Yujuan Li 1 · Xianghe Meng 1 · Liyuan Du 1 lowest paid mlb contract

"WebNov 16, 2024 · FAM134B (also called JK-1, RETREG1), a member of the family with sequence similarity 134, was originally discovered as an oncogene in esophageal … " - Cst fam134b

Cst fam134b

FAM134B oligomerization drives endoplasmic reticulum membrane scission ...

WebJun 23, 2024 · The recent identification of FGF/TFEB/FAM134B signaling event represents the first study that implicates the role of TFEB in ER-phagy and its physiological relevance during skeletal development in ... Highly specific and rigorously validated in-house, FAM134B (E8Y9R) Rabbit Monoclonal Antibody (CST #83414) is ready to ship. ... FAM134B (family with sequence similarity 134, member B), also referred to as JK-1 and RETREG1, is a cis-Golgi endoplasmic reticulum (ER) transmembrane protein that plays a role in ER homeostasis and may contribute to ...

Did you know?

WebDec 31, 2024 · Department of the Treasury Internal Revenue Service Cincinnati, OH 45999-0039 Notice CP134B Tax period December 31, 2024 Notice Date January 8, 2024 … WebDec 16, 2024 · The Fam134b gene, located on chromosome 5p15.1, was first identified as a regulator of the malignant phenotype and a downstream molecule of δ-catenin in esophageal squamous cell carcinoma (Tang et al., 2007). However, in colon cancer, FAM134B inhibits the migration of tumor cells (Kasem et al., 2014a, b).

WebAug 24, 2024 · Several ER surface receptors, including FAM134B, reticulon 3L (RTN3L), Sec62, and CCPG1, have been shown to contain conserved LC3-interacting regions (LIRs) that can act as specific autophagy receptors to allow portions of the larger ER network to be shunted to core autophagy pathways ( Khaminets et al., 2015; Fumagalli et al., 2016; … WebMar 29, 2024 · Fam134b is an oncogene that plays a crucial role in hepatocellular carcinoma via the Akt signaling pathway. FAM134B could play crucial roles in the …

WebFAM134B (E8Y9R) Rabbit mAb Cell Signaling Technology Monoclonal Antibody for studying FAM134B. Validated for WB, IP, IF. Highly specific and rigorously validated in-house, FAM134B (E8Y9R) Rabbit Monoclonal Antibody (CST #83414) is ready to ship. Go to your regional site? Would you like to visit your country specific website? YESNO WebDec 14, 2024 · FAM134B (also called RETREG1) is a critical gene for neuronal survival. FAM134B loss-of-function mutations cause hereditary sensory and autonomic neuropathy type II, and its knockdown results in structural alterations of the cis -Golgi compartment, inducing apoptosis in some primary dorsal root ganglion neurons ( 25 ).

WebAug 6, 2024 · FAM134B is the first identified ER-phagy receptor that involves in ER fragments and ER-resident protein clearance in mammalian cells; moreover, dysfunction of FAM134B has been reported to be …

WebOct 4, 2016 · FAM134B, the Selective Autophagy Receptor for Endoplasmic Reticulum Turnover, Inhibits Replication of Ebola Virus Strains Makona and Mayinga Abhilash I. Chiramel, Jonathan D. Dougherty, Vinod Nair, Shelly J. Robertson, Sonja M. Best jane russell movies and tv showsWebFam134b, supplied by Abcam, used in various techniques. Bioz Stars score: 92/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more jane ruth aceng minister of healthWebJun 3, 2015 · ER-bound FAM134B interacts with a protein called LC3 in phagophores through an LIR domain, leading to engulfment of ER fragments by autophagosomes. Mochida et al . 2 report that Atg39 and Atg40 ... jane russell the outlaws brassiereWebJan 13, 2024 · FAM134B forms oligomers that are required for ER membrane scission and ER-phagy A. Endogenous FAM134B forms oligomers. FAM134B knockout (KO) or wild-type (WT) 293T cells were treated with 1 μM of Thapsigargin (Tg) for different time, and the cell lysates were prepared and analyzed by Western blot. jane russell the palefaceWebFAM134B (family with sequence similarity 134, member B), also referred to as JK-1 and RETREG1, is a cis-Golgi endoplasmic reticulum (ER) transmembrane protein that plays a role in ER homeostasis and may … jane russell the french line danceWebJul 8, 2024 · The endoplasmic reticulum (ER) autophagy receptor FAM134B contains an LIR motif that can bind to Atg8s, but whether it can differentially bind to the two … jane ruth achengWebThe protein encoded by FAM134B is a reticulophagy receptor that regulates turnover of the endoplasmic reticulum (ER) by selective phagocytosis. Absence or non-functional … jane ruth aceng