WebSep 30, 2024 · 이뮤노메딕스 (Immunomedics)는 트로델비 (Trodelvy)를 개발하는데 약간 과발현된 표적을 타겟팅을 하고, 종전의 MMAE나 DM1과 같은 약물보다 더 독성이 약한 약물을 채택하고, 약물이 세포 내부 및 세포 외부에서 모두 방출이 되게 하였다. 2024년 US FDA에서 승인을 받은 트로델비 (Trodelvy)에서는 항-TROP2 단일클론항체에 … WebApr 12, 2024 · 4. Binance Coin (BNB) Market cap: $48.9 billion. Binance Coin (BNB) is a form of cryptocurrency that you can use to trade and pay fees on Binance, one of the largest …
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WebJun 29, 2024 · 隐粘菌素(Cryptomycins,CR)是一个具有抗肿瘤活性的六元大环二肽家族。 已有的临床试验的结果表明,在达到治疗效果所需的剂量下,其毒性水平是不可接受的。 几个小组尝试将CR用于ADC,但是由于在CR中缺少偶联位点,目前,有两种不同的方法通过引入其它基团,使得能够连接ADC的连接子。 一种是由基因泰克的研究人员将苯转化为 … WebSep 26, 2024 · Ether, launched in 2015, is currently the second-largest digital currency by market capitalization after Bitcoin, although it lags behind the dominant cryptocurrency by … flowers that rabbits won\u0027t eat
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